1. Formulated and announced in 19 articles by the Department of Health, the Executive Yuan, on September 26, 2005, under Shu-Shou-Chi Order No. 0940000614; and implemented as of March 26, 2006.
2. Amended and announced Article 2-1 and Article 19 on April 11, 2006, by the Department of Health, the Executive Yuan, under Shu-Shou-Chi Order No. 0950000194
3. Amended the title (original title: Regulations Governing Management of Infectious Biological Materials and Collection of Specimens from Patients of Communicable Diseases) and 21 articles, and announced by the Ministry of Health and Welfare on March 11, 2014 under Bu-Shou-Chi Order No. 1030100208
4. Amended the title and 21 articles, and announced by the Ministry of Health and Welfare on December 13, 2016 under Bu-Shou-Chi Order No. 1050101528
5. Amended and promulgated in 39 articles by the Ministry of Health and Welfare on January 31, 2019 and implemented on the date of promulgation under Bu-Shou-Chi Order No. 1080100040
6. Amended and promulgated in 44 articles by the Ministry of Health and Welfare on December 15, 2021, under Bu-Shou-Chi Order No. 1100102022; the amended articles shall be implemented on the date of promulgation, except for Article 11 and paragraph 2 of Article 32, implemented on January 1, 2025, and Article 19, implemented one year after promulgated.